PoCoG Supported Studies open to recruitment

PoCoG-2009-11: The CHALLENGE Trial. A Phase III Study of the Impact of a Physical Activity Program on Disease-Free Survival in Patient with High Risk Stage II or Stage III Colon Cancer: A Randomised Controlled Trial

Aim:

To determine the efficacy of Physical Activity in reducing disease recurrence in patients with localised colon cancer.

Primary Investigator
Chief Investigators
Janette Vardy Stephen Clarke
  Haryana Dhillon

Study contact: Shelley.Kay@sydney.edu.au

PoCoG-2010-06: Efficacy and safety of Gingko biloba for cognitive function and fatigue in breast cancer patients undergoing adjuvant chemotherapy

Aim:

This is prospective, longitudinal, placebo-controlled randomised controlled trial will evaluate the effects of the traditional Chinese herbal medicine Ginkgo biloba on cognitive dysfunction and fatigue associated with adjuvant chemotherapy in breast cancer survivors. The study will also investigate the underlying mechanisms of fatigue and cognitive impairment, and evaluate possible interactions between Gingko biloba and the common chemotherapy drugs used to treat breast cancer. Pharmacological sub-studies will obtain pharmacokinetic and pharmacodynamic information about Gingko biloba and any interaction with chemotherapy and hormonal anti-cancer treatment respectively.

Primary Investigator
Chief Investigators
Janette Vardy  Haryana Dhillon
  Melanie Bell
  Andrew McLachlan
  Stephen Clarke
  Fran Boyle
   

Study contact: Haryana.Dhillon@sydney.edu.au

PoCoG-2013-02: Rekindle Sexuality After Cancer: Development and Testing of a Novel Web-Based Psycho-educational Resource for BOTH Survivors and their Partners

Aim:

To develop and evaluate a web-based intervention to address sexual concerns amongst individuals with all cancer types.

Primary Investigator
Chief Investigators
Haryana Dhillon Catalina Lawsin
  Phyllis Butow
  Ilona Juraskova
  Kim Hobbs
  Sylvie Lambert
  Judy Kay
  Kevin McGeechan
  Fran Boyle
  Lori Brotto

Study contact: Douglas.Williams@sydney.edu.au   

PoCoG-2013-04: Cognitive rehabilitation for breast cancer survivors with perceived cognitive impairment

Aims:

To evaluate two cognitive rehabilitation programmes in localised breast cancer survivors with perceived cognitive dysfunction after chemotherapy: (1) a structured neurocognitive learning programme (Attention Process Training [APT], aimed at improving underlying cognitive deficit) and (2) a systematic teaching of strategies to compensate for the functional impact of cognitive deficits (Compensatory Strategy Training [CST]).

Primary Investigator
Chief investigators
Janette Vardy       Melanie Bell
  Melanie Price
  Haryana Dhillon

Study contact: Haryana.Dhillon@sydney.edu.au

PoCoG-2013-05*: An observational study of health-related quality of life in people with malignant mesothelioma

Aim:

To explore the course of HQoL in different groups of people with malignant mesothelioma throughout the disease trajectory. It will provide information regarding supportive care needs and other psychological factors that contribute to HQoL outcomes.

Primary Investigator
Chief investigators
Janette Vardy Steven Kao
  Haryana Dhillon
  Jason Fowler
  Melanie Price
  Anne Warby
  Sim (Cindy) Tan
  Jocelyn McLean

Study contact: Jason.Fowler@sydney.edu.au

*In collaboration with: Australasian Lung Trials Group (ALTG)                     

PoCoG-2015-01: Cancer Nutrition and Exercise rehabilitation program (CaNE) for patients with advanced cancer at risk of cancer cachexia syndrome - a phase II feasibility study

Aims:

To (1)determine the feasibility of a 12-week supervised resistance exercise program with protein and fish oil supplements in patients with advanced upper gastrointestinal (UGI) cancer or lung cancer; (2) determine the functional status, nutritional status and quality of life (QoL) of patients with advanced cancer at risk of developing the cancer cachexia syndrome; (3) evaluate whether a nutritional and exercise intervention can improve or delay onset of cancer cachexia in at risk patients and (4) observe patients’ clinical and biochemical parameters pre- and post- intervention and during the follow up period.

Primary Investigator
Chief Investigators
Janette Vardy  Cindy Tan
  Prunella Blinman
  Jane Turner
  Haryana Dhillon
  Amanda Salis

Study contact: Cindy.Tan@sswahs.nsw.gov.au