PoCoG Supported Studies - CONCEPTS Developed 2017-18


PoCoG-2018-01: Large-scale data to understand person-centred outcomes in cancer survivors.


Aim: This study aims to create a population-based high-quality data platform for person-centred cancer survivorship research comprising linked individual questionnaire, cancer registry, hospitalisation, medication, primary care and mortality data from the 45 and Up Study and newly generated qualitative data, incorporating state-of-the-art validation and methodological development. Qualitative research methods will be used to understand in-depth elements of the lived experience of long-term cancer survivorship, building on quantitative findings in order to identify interventions for implementation at practice, community and policy levels to maximise the health and wellbeing of cancer survivors.


Investigator Team: Emily Banks, Phyllis Butow, Bogda Koczwara, Grace Joshy, Rebecca Laidsaar-Powell, Nicole Rankin, Wei Du

Status: In development


PoCoG-2018-02: “Scanxiety”: Scan-associated anxiety in patients with solid tumours


Aim: The study will examine: (1) Prevalence of scanxiety in patients with early (potentially curable) cancer or advanced (incurable) cancer in an outpatient oncology clinic, (2) Factors associated with the presence and severity of scanxiety and (3) Patients’ and health professionals’ perceptions of scanxiety including possible interventions


Investigator Team: Kim Tam Bui, Prunella Blinman, Belinda Kiely, Haryana Dhillon, Christopher Brown

Status: In development


PoCoG-2018-04 : Advancing Psychological Treatments for People with Stage III or IV Melanoma: A Multi-State Phase III Randomised Controlled Trial.


Aim: This project will take a model that we have shown to be highly effective, safe and feasible for use with people with early stage melanoma, make the necessary and appropriate modifications for application in the advanced melanoma setting, and evaluate it using a phase III randomised controlled trial with in-built economic evaluation. The primary aim of the project is to assess the efficacy of a multi-faceted, patient-centred psychological intervention for people diagnosed with Stage III or IV melanoma in the past two years and assessed as medically-stable or treatment-responding for at least 3 months at the time of study invitation.


Investigator Team: Nadine Kasparian Rachael Morton, Anne Cust, Scott Menzies, Robyn Saw, Phyllis Butow, Graham Mann, Victoria Atkinson, Daniel Costa, Alex Menzies, Mark Smithers, Chris Allan, David Gyorki, Donna Milne, Fiona Bennett, Georgina Long, Grant McArthur, Michael Henderson, Mbathio Dieng, Susan Suchy

Status: Awaiting funding


PoCoG- 2018-03: Clinician Intervention to Reduce Fear of Recurrence in Cancer Survivors (CIFeR Study)


Aim: To trial a novel clinician-driven education intervention which can be practically introduced in the context of surveillance clinic visits to help patients manage FCR. This study hypotheses that: 1) A brief 4-step intervention can be feasibly incorporated into routine surveillance clinics by clinicians without adding significantly to the consultation time to address patients’ FCR. 2) The brief intervention is able to reduce FCR in patients with mild-moderate levels of baseline FCR and improves communication between patients and clinicians.


Investigator Team: Jia (Jenny) Liu, Jane Beith, Phyllis Butow, Belinda Kiely, Annabelle Goodwin, Mun Hui, Catriona McNeil

Status: In development


PoCoG-2018-07: Early detection of chemotherapy-induced cardiomyopathy


Aim: This study will follow-up patients who have a diagnosis of cancer and are about to begin chemotherapy, known to cause cardiotoxicity. The aim of this study is to identify patients who have subclinical evidence of early cardiac dysfunction based on the biomarker testings to enable early prevention of further possibly irreversible deterioration and/or change of chemotherapy agents.


Investigator Team: Aaaron Sverdlov and Doan Ngo

Status: In development


PoCoG-2011-07: ConquerFear Advanced: A randomized control trial to reduce fear of cancer recurrence in patients with advanced disease


Aim: To evaluate in a randomised controlled trial, the efficacy of an intervention (Conquer Fear Advanced) based on a novel model of cancer-related anxiety and a proven intervention, in reducing the impact of fear of cancer recurrence (FCR) in cancer survivors with advanced disease.


Investigator Team: Louise Sharpe, Phyllis Butow, Jane Turner, Belinda Thewes, Jane Beith, Ben Smith

Status: Awaiting funding


PoCoG-2011-09:  iConquerFear: A randomised controlled trial of an online self-management intervention to reduce fear of cancer recurrence


Aim: To evaluate the efficacy of iConquerFear, an online self-management intervention, in reducing fear of cancer recurrence (FCR) severity (primary outcome) and ameliorating FCR-related outcomes including cancer-related distress, anxiety, depression, and healthcare utilisation/costs (secondary outcomes), in curatively-treated cancer survivors, compared with an attention control (online relaxation training) in a randomised controlled trial (RCT).


Investigator Team: Ben Smith

Status: Awaiting funding