PoCoG Supported Studies - CONCEPTS Developed 2019-20


PoCoG-2011-07: ConquerFear Advanced: A randomized control trial to reduce fear of cancer recurrence in patients with advanced disease


Aim: To evaluate in a randomised controlled trial, the efficacy of an intervention (Conquer Fear Advanced) based on a novel model of cancer-related anxiety and a proven intervention, in reducing the impact of fear of cancer recurrence (FCR) in cancer survivors with advanced disease.


Investigator Team: Louise Sharpe, Phyllis Butow, Jane Turner, Belinda Thewes, Jane Beith, Ben Smith

Status: Awaiting funding


PoCoG-2011-09:  iConquerFear: A randomised controlled trial of an online self-management intervention to reduce fear of cancer recurrence


 Aim: To evaluate the efficacy of iConquerFear, an online self-management intervention, in reducing fear of cancer recurrence (FCR) severity (primary outcome) and ameliorating FCR-related outcomes including cancer-related distress, anxiety, depression, and healthcare utilisation/costs (secondary outcomes), in curatively-treated cancer survivors, compared with an attention control (online relaxation training) in a randomised controlled trial (RCT).


Investigator Team: Ben Smith, Louise Sharpe, Phyllis Butow, Jane Turner, Belinda Thewes, Jane Beith

Status: Awaiting funding


PoCoG-2018-15: Light Enhanced Cognitive Behavioural Therapy (CBT+) for Sleep and Fatigue: A Randomized Controlled Trial during Chemotherapy for Cancer


Aim: Aim 1 Test the efficacy of cognitive behavioural and bright light therapy (CBT+) compared to relaxation audio and basic psychoeducation (CONTROL) for improving symptoms of sleep disturbance and fatigue. Aim 2 Test the efficacy of CBT+ versus CONTROL for psychological outcomes. Aim 3 Exploratory aim to test potential mechanisms and moderators of the intervention efficacy.


Investigator Team: Joshua Wiley, Bei Bei, Sheila Garland, Sonia Ancoli-Israel, Haitham Tuffaha

Status: In development


PoCoG-2019-201: Ensuring equity and access to optimal health care: Applying patient reported outcome measures to guide resource allocation, health system performance and individual care.


Aim: To develop systematic approaches to routine application of PROMs accessible to all, with provision of meaningful individual and aggregated PROMs data to patients, clinicians and health system decision makers, to influence all levels of healthcare.


Investigator team: Phyllis Butow, Rosalie Viney, Gail Garvey, Haryana Dhillon, Joanne Shaw

Status: On hold


PoCoG-CDW-2019-02: Randomised control trial of a multi-disciplinary intervention for the management of fatigue in community palliative care: A feasibility study


Aim: To determine the feasibility of a multi-modal intervention for fatigue in patients with advanced life-limiting illness referred to a community palliative care setting


Investigator team: Dr Gemma Ingham, Dr Katalin Urban

Status: In development by CST


PoCoG-2019-401: iScreen - every cancer patient every need


Aim: To implement a systemic approach to online screening of cancer patients for their unmet needs and distress and address these needs using an evidence-based clinical pathway.


Investigator team: Bogda Koczwara, Phyllis Butow, Lisa Beatty, Joanne Shaw, Heather Shepherd, Haryana Dhillon

Status: In development


PoCoG-CDW-2019-01: Cancer-Related Fatigue Clinic Study


Aim: Phase 1: To develop a CRF Clinic Model of Care and test the feasibility and acceptability of a CRF Clinic and Phase 2: To test the effectiveness of the CRF Clinic compared to usual care and to test the cost-effectiveness of a CRF Clinical model of care compared to usual care.


Investigator team: Ray Chan, Patsy Yates, Carmelita Escalante

Status: In development


PoCoG-CDW-2019-05: Reducing CVD risk after a cancer diagnosis among indigenous and non-indigenous Australians


Aim: To provide a systems-wide perspective of CVD in cancer, by investigating, for NSW residents diagnosed with cancer over a 10-year period:

·         The prevalence of pre-existing and treatment-induced CVD in people diagnosed with cancer and its effect on their clinical course, outcomes and health care use/cost

·         Variations in the above between Aboriginal and Torres Strait Islander people and non-Indigenous people, and by country of birth, sex, age group, cancer type, remoteness and area-level socioeconomic status.


Investigator Team: Abbey Diaz, Aaron Sverdlov Kalinda Griffiths Joanne Shaw Doan Ngo Joan Cunningham Brian Kelly Gail Garvey Emily Callander Lisa Whop Nick Zdenkowski

Status: Awaiting funding


PoCoG-2019-05: Phase II trial evaluating web-based cognitive behaviour for sleep disturbance in early stage breast cancer patients on (neo) adjuvant chemotherapy


Aim: To assess the feasibility and acceptability of web-based cognitive behaviour for sleep disturbance in early stage breast cancer patients during treatment.


Investigator Team: Emma-Kate Carson, Belinda Kiely, Janette Vardy, Haryana Dhillon

Status: In development


PoCoG-2020-03: LATER (life after cancer) Study: Online platform for managing symptoms


Aim: To develop and evaluate an online platform delivering evidence-based interventions to reduce common symptoms matched to individual need for women cancer patients to improve quality of life.


Investigator Team: Michelle Peate, Martha Hickey, Jennifer Marino, Michael Jefford, Christobel Saunders, Debra Anderson, Michael Friedlander, Bruce Mann, Ines Rio, Nicole Kinnane

Status: Awaiting funding


PoCoG-2020-02: Impact of the COVID-19 pandemic on care of patients with cancer and multimorbid conditions


Aim: To ensure the delivery of patient-centred care in the face of COVID-19 and beyond, understanding patient perceptions and experiences is crucial. Our aim is to capture perceptions, experiences and concerns about cancer and multimorbidity management now and over the next 3-12 months.


Investigator Team: Jasmine Yee, Haryana Dhillon, Bogda Koczwara, Jon Emery, Claudia Rutherford, Raymond Chan, Kristi Milley, Sharon Lawn

Status: In development